Streptococcal co‐infection augments <i> <scp>C</scp> andida </i> pathogenicity by amplifying the mucosal inflammatory response

Abstract excerpt

Mitis-group streptococci are ubiquitous oral commensals that can promote polybacterial biofilm virulence. Using a novel murine oral mucosal co-infection model we sought to determine for the first time whether these organisms promote the virulence of C. albicans mucosal biofilms in oropharyngeal infection and explored mechanisms of pathogenic synergy. We found that Streptococcus oralis colonization of the oral and...

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