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Article

Germ-line deletion in DICER1 revealed by a novel MLPA assay using synthetic oligonucleotides.

European journal of human genetics : EJHG - 1 Apr 2014

Sabbaghian Nelly, Srivastava Archana, Hamel Nancy, Plourde François, Gajtko-Metera Malgorzata, Niedziela Marek, Foulkes William D

Abstract excerpt

DICER1 is an endoribonuclease responsible for the production of mature microRNAs which are small, single-stranded RNA molecules that regulate gene expression post-transcriptionally by binding to mRNA and repressing the expression of target genes. Germ-line mutations in DICER1 are responsible for...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 24065110
DOI: 10.1038/ejhg.2013.215
PMCID: PMC3953921

Genes

DICER1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24065110-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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