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Chloramphenicol acetyltransferase as a selection marker for chlamydial transformation

23 Sept 2013

Abstract excerpt

BACKGROUND: Chlamydia is a common bacterial pathogen responsible for many diseases. Methods for transforming this important organism using a β-lactamase as a selection marker have been developed very recently. However, the National Institutes of Health Guidelines for Research Involving Recombinant DNA Molecules do not permit transformation experiments with β-lactamase gene-containing vectors for certain human...

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PMID: 24060200
DOI: 10.1186/1756-0500-6-377

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