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Article

Computational analysis of TRAPPC9: candidate gene for autosomal recessive non-syndromic mental retardation.

CNS & neurological disorders drug targets - 1 Jan 2014

Khattak Naureen Aslam, Mir Asif

Abstract excerpt

Mental retardation (MR)/ intellectual disability (ID) is a neuro-developmental disorder characterized by a low intellectual quotient (IQ) and deficits in adaptive behavior related to everyday life tasks such as delayed language acquisition, social skills or self-help skills with onset before age 18. To date, a few genes (PRSS12, CRBN, CC2D1A, GRIK2, TUSC3, TRAPPC9, TECR, ST3GAL3, MED23, MAN1B1, NSUN1) for...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24040793
DOI: 10.2174/18715273113129990105

Genes

TRAPPC9
CRBN
GRIK2
MED23
PRSS12
TECR
TUSC3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

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Computational analysis of TRAPPC9: candidate gene for autosomal recessive non-syndromic mental retardation.PMID 24040793Read ↗

Identification of two novel homozygous nonsense mutations in TRAPPC9 in two unrelated consanguineous families with intellectual Disability from Iran.Semantic proximity Read ↗

Identification of mutations in TRAPPC9, which encodes the NIK- and IKK-beta-binding protein, in nonsyndromic autosomal-recessive mental retardation.Semantic proximity Read ↗

TRAPPC9-related autosomal recessive intellectual disability: report of a new mutation and clinical phenotype.Semantic proximity Read ↗

[Diagnosis of a case with mental retardation due to novel compound heterozygous variants of TRAPPC9 gene].Semantic proximity Read ↗

Expanding the genetic and phenotypic spectrum of TRAPPC9 and MID2-related neurodevelopmental disabilities: report of two novel mutations, 3D-modelling, and molecular docking studies.Semantic proximity Read ↗

A novel homozygous mutation in TRAPPC9 gene causing autosomal recessive non-syndromic intellectual disability.Semantic proximity Read ↗

Introducing a novel TRAPPC10 gene variant as a potential cause of developmental delay and intellectual disability in an Iranian family.Semantic proximity Read ↗

The <i>CC2D1A</i>, a member of a new gene family with C2 domains, is involved in autosomal recessive non-syndromic mental retardationSemantic proximity Read ↗

Introducing a novel homozygote TRAPPC10 mutation as a potential cause of developmental delay and intellectual disability in an Iranian familySemantic proximity Read ↗

Identification of a Novel Mutation in CTCF in a Family with MRD21Semantic proximity Read ↗

A truncating mutation of TRAPPC9 is associated with autosomal-recessive intellectual disability and postnatal microcephaly.Semantic proximity Read ↗

Candidate genes for recessive non-syndromic mental retardation on chromosome 3p (MRT2A).Semantic proximity Read ↗

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