Article
Association of the MTHFR 1298A>C (rs1801131) polymorphism with speed and strength sports in Russian and Polish athletes.
Journal of sports sciences - 1 Jan 2014
Zarebska Aleksandra, Ahmetov Ildus I, Sawczyn Stanislaw, Weiner Alexandra S, Kaczmarczyk Mariusz, Ficek Krzysztof, Maciejewska-Karlowska Agnieszka, Sawczuk Marek, Leonska-Duniec Agata, Klocek Tomasz, Voronina Elena N, Boyarskikh Uljana A, Filipenko Maksim L, Cieszczyk Pawel
Abstract excerpt
It has been suggested that DNA hypomethylation because of poorer effectiveness of the 5,10-methylenetetrahydrofolate reductase (MTHFR) enzyme induces muscular growth. We hypothesised that the common, functional 1298A>C polymorphism in the MTHFR gene is associated with athletic status. To test this hypothesis, we investigated the distribution of the 1298A>C variant in Polish (n = 302) and Russian (n = 842)...
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