Article
Assessment of umbilical cord tissue as a source of mesenchymal stem cell/endothelial cell mixtures for bone regeneration.
Regenerative medicine - 1 Sept 2013
Kouroupis Dimitrios, Churchman Sarah M, English Anne, Emery Paul, Giannoudis Peter V, McGonagle Dennis, Jones Elena A
Abstract excerpt
AIM: To enumerate and characterize mesenchymal stem cells (MSCs) and endothelial cells (ECs) in umbilical cord (UC) tissue digests. MATERIALS & METHODS: Cultured UC cells were characterized phenotypically, and functionally by using 48-gene arrays. Native MSCs and ECs were enumerated using flow cytometry. RESULTS: Compared with bone marrow (BM) MSCs, UC MSCs displayed significantly lower (range 4-240-fold) basal...
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