Article
STROGAR - STrengthening the Reporting Of Genetic Association studies in Radiogenomics.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology - 1 Jan 2014
Kerns Sarah L, de Ruysscher Dirk, Andreassen Christian N, Azria David, Barnett Gillian C, Chang-Claude Jenny, Davidson Susan, Deasy Joseph O, Dunning Alison M, Ostrer Harry, Rosenstein Barry S, West Catharine M L, Bentzen Søren M
Abstract excerpt
Despite publication of numerous radiogenomics studies to date, positive single nucleotide polymorphism (SNP) associations have rarely been reproduced in independent validation studies. A major reason for these inconsistencies is a high number of false positive findings because no adjustments were made for multiple comparisons. It is also possible that some validation studies were false negatives due to...
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