Article
Comprehensive genotyping for 18 blood group systems using a multiplex ligation-dependent probe amplification assay shows a high degree of accuracy.
Transfusion - 1 Nov 2013
Haer-Wigman Lonneke, Ji Yanli, Lodén Martin, de Haas Masja, van der Schoot C Ellen, Veldhuisen Barbera
Abstract excerpt
BACKGROUND: In recent years genotyping methods have been implemented in blood banks as alternative to comprehensive serologic typing. We evaluated a newly developed assay for convenient and comprehensive genotyping of blood group alleles based on multiplex ligation-dependent probe amplification (MLPA) technology. STUDY DESIGN AND METHODS: We analyzed 103 random and 150 selected samples to validate the specificity...
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