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Secretome of Transmissible <i>Pseudomonas aeruginosa</i> AES-1R Grown in a Cystic Fibrosis Lung-Like Environment

30 Aug 2013

Abstract excerpt

Pseudomonas aeruginosa is the predominant cause of mortality in patients with cystic fibrosis (CF). We examined the secretome of an acute, transmissible CF P. aeruginosa (Australian epidemic strain 1-R; AES-1R) compared with laboratory-adapted PAO1. Culture supernatant proteins from rich (LB) and minimal (M9) media were compared using 2-DE and 2DLC-MS/MS, which revealed elevated abundance of PasP protease and...

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PMID: 23991618
DOI: 10.1021/pr4007365

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