Article
Yield of molecular and clinical testing for arrhythmia syndromes: report of 15 years' experience.
Circulation - 1 Oct 2013
Hofman Nynke, Tan Hanno L, Alders Mariëlle, Kolder Iris, de Haij Simone, Mannens Marcel M A M, Lombardi Maria Paola, Dit Deprez Ronald H Lekanne, van Langen Irene, Wilde Arthur A M
Abstract excerpt
BACKGROUND: Sudden cardiac death is often caused by inherited arrhythmia syndromes, particularly if it occurs at a young age. In 1996, we started a cardiogenetics clinic aimed at diagnosing such syndromes and providing timely (often presymptomatic) treatment to families in which such syndromes or sudden cardiac death existed. We studied the yield of DNA testing for these syndromes using a candidate-gene approach...
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