Article
Safety and efficacy of faldaprevir with pegylated interferon alfa-2a and ribavirin in Japanese patients with chronic genotype-1 hepatitis C infection.
Liver international : official journal of the International Association for the Study of the Liver - 1 Jan 2014
Nishiguchi Shuhei, Sakai Yoshiyuki, Kuboki Makoto, Tsunematsu Satoshi, Urano Yasuhisa, Sakamoto Wataru, Tsuda Yasuhiro, Steinmann Gerhard, Omata Masao
Abstract excerpt
BACKGROUND & AIMS: Faldaprevir (BI 201335) is a potent once-daily (QD) NS3/4A protease inhibitor for the treatment of patients with genotype-1 (GT-1) hepatitis C virus (HCV). The aim of this study was to evaluate the safety, pharmacokinetics and efficacy of faldaprevir plus pegylated interferon alfa-2a (PegIFN) and ribavirin (RBV) in Japanese patients infected with chronic GT-1 HCV. METHODS: Part 1 of this phase...
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