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Article

Biologic approaches to drug selection and targeted therapy: hype or clinical reality?

Thoracic surgery clinics - 1 Aug 2013

Wigle Dennis A

Abstract excerpt

Oncology remains at the forefront of the application of individualized or genomics-driven approaches to cancer care. This approach acknowledges cancer as a genetic disease, driven by alterations in oncogenes and tumor suppressors, with the strategy of using this information to guide therapy based on therapeutics capable of targeting specific alterations. Recent advances suggest a changing landscape in how...

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PMID: 23931024
DOI: 10.1016/j.thorsurg.2013.05.003

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