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Article

Identification of a novel DRB1 allele through intergenic recombination between HLA-DRB1 and HLA-DRB3∗02 in a Chinese family.

Human immunology - 1 Dec 2013

Huang Weijin, Liu Xiangjun, Li Erwei, Zhao Chenyan, Liu Qiang, Liang Zhenglun, Wang Youchun, Lu Fengmin

Abstract excerpt

In this study, a novel DRB1 allele was revealed by routine HLA-SBT typing noted for its extensive mismatches to any known DRB1 alleles within the exon 2. Sequences containing the exons 2, 3 of HLA-DRB1, their surrounding introns, and the full-length cDNA of DRB1 were analyzed to determine a possible recombination event. Interestingly, the sequences of entire exon 2 were characterized as DRB3(∗)02:02:01:01/02;...

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Identifiers

PMID: 23911361
DOI: 10.1016/j.humimm.2013.07.013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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