Article
Mining the bacterial unknown proteome: identification and characterization of a novel family of highly conserved protective antigens in <i>Staphylococcus aureus</i>
30 Jul 2013
Abstract excerpt
In the human pathogen Staphylococcus aureus, there exists an enormous diversity of proteins containing DUFs (domains of unknown function). In the present study, we characterized the family of conserved staphylococcal antigens (Csa) classified as DUF576 and taxonomically restricted to Staphylococci. The 18 Csa paralogues in S. aureus Newman are highly similar at the sequence level, yet were found to be expressed...
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