Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Engineering animal models of dystonia

15 Jun 2013

Abstract excerpt

Dystonia is a neurological disorder characterized by abnormal involuntary movements that are prolonged and often cause twisting and turning. Several genetically modified worms, fruit flies, and rodents have been generated as models of genetic dystonias, in particular DYT1, DYT11, and DYT12 dystonias. Although these models do not show overt dystonic symptoms, the rodent models exhibit motor deficits in specialized...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic Neurodegenerative Diseases
Share to Neurological disorders and treatments
Share to Neuroscience and Neural Engineering

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 23893455
DOI: 10.1002/mds.25583

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Engineering animal models of dystoniaPMID 23893455Read ↗

Experimental models of dystonia.Semantic proximity Read ↗

Generation of a novel rodent model for DYT1 dystoniaSemantic proximity Read ↗

Rodent models for dystonia research: characteristics, evaluation, and utility.Semantic proximity Read ↗

Animal models for dystoniaSemantic proximity Read ↗

Transgenic mouse model of early-onset DYT1 dystoniaSemantic proximity Read ↗

Genetics and pharmacological treatment of dystonia.Semantic proximity Read ↗

A new knock-in mouse model of l-DOPA-responsive dystonia.Semantic proximity Read ↗

Models of dystonia: an update.Semantic proximity Read ↗

A dystonia mouse model with motor and sequencing deficits paralleling human disease.Semantic proximity Read ↗

Generation and characterization of Dyt1 ΔGAG knock-in mouse as a model for early-onset dystoniaSemantic proximity Read ↗

[Dystonia].Semantic proximity Read ↗

Implantation of Osmotic Pumps and Induction of Stress to Establish a Symptomatic, Pharmacological Mouse Model for DYT/PARK-ATP1A3 Dystonia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.