Article
Assessment of the association between XRCC1 Arg399Gln polymorphism and lung cancer in Chinese.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Dec 2013
Li Yi, Huang Yi, Cao Yu-Shu, Zeng Jia, Tong Wan-Ning, Xu Shi-Lin, Zhuo An-Shan
Abstract excerpt
X-ray repair cross-complementing group 1 (XRCC1) is one of the major DNA repair proteins involved in the base excision repair and plays an important role in the maintenance of genomic integrity. Polymorphisms in XRCC1 may alter the function and repair capacity of XRCC1 protein which further results in the genetic instability and lung carcinogenesis. Previous studies investigating the relationship between XRCC1...
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