Article
Association between the luteinizing hormone/chorionic gonadotropin receptor (LHCGR) rs4073366 polymorphism and ovarian hyperstimulation syndrome during controlled ovarian hyperstimulation.
Reproductive biology and endocrinology : RB&E - 25 Jul 2013
O'Brien Travis J, Kalmin Mariah M, Harralson Arthur F, Clark Adam M, Gindoff Ian, Simmens Samuel J, Frankfurter David, Gindoff Paul
Abstract excerpt
BACKGROUND: The aim of this study was to determine the relationship between a purported luteinizing hormone/chorionic gonadotropin (LHCGR) high function polymorphism (rs4539842/insLQ) and outcome to controlled ovarian hyperstimulation (COH). METHODS: This was a prospective study of 172 patients undergoing COH at the Fertility and IVF Center at GWU. DNA was isolated from blood samples and a region encompassing the...
Topics
- Adult
- Aging
- Female
- Gene Frequency
- Humans
- Linkage Disequilibrium
- Ovarian Hyperstimulation Syndrome