Article
[Advanced Parkinson's disease: clinical characteristics and treatment (part 1)].
Neurologia (Barcelona, Spain) - 1 Oct 2013
Kulisevsky J, Luquin M R, Arbelo J M, Burguera J A, Carrillo F, Castro A, Chacón J, García-Ruiz P J, Lezcano E, Mir P, Martinez-Castrillo J C, Martínez-Torres I, Puente V, Sesar A, Valldeoriola-Serra F, Yañez R
Abstract excerpt
INTRODUCTION: A large percentage of patients with Parkinson's disease (PD) develop motor fluctuations, dyskinesias, and severe non-motor symptoms within 3 to 5 years of starting dopaminergic therapy, and these motor complications are refractory to treatment. Several authors refer to this stage of the disease as advanced Parkinson's disease. OBJECTIVE: To define the clinical manifestations of advanced PD and the...
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