Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genistein Down-Regulates miR-223 Expression in Pancreatic Cancer Cells

1 Jul 2013

Abstract excerpt

Although genistein has been shown to inhibit tumorigenesis in a variety of human cancers including pancreatic cancer (PC), the exact molecular mechanism of its anti-cancer effects has not yet been fully elucidated. Recently, microRNAs (miRNAs) have been reported to regulate multiple aspects of tumor development and progression, indicating that targeting miRNAs could be a novel strategy to treat human cancers. In...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related molecular mechanisms research
Share to MicroRNA in disease regulation
Share to Phytoestrogen effects and research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 23834147
DOI: 10.2174/13894501113149990187

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genistein Down-Regulates miR-223 Expression in Pancreatic Cancer CellsPMID 23834147Read ↗

Genistein Inhibits Cell Growth and Invasion Through Regulation of miR-27a in Pancreatic Cancer CellsSemantic proximity Read ↗

Flavonoids as modulators of miRNA expression in pancreatic cancer: Pathways, Mechanisms, And Therapeutic PotentialSemantic proximity Read ↗

Ursolic Acid Inhibits the Proliferation of Gastric Cancer Cells by Targeting miR-133aSemantic proximity Read ↗

Improving Gemcitabine Sensitivity in Pancreatic Cancer Cells by Restoring miRNA-217 LevelsSemantic proximity Read ↗

Genistein downregulates onco-miR-1260b and upregulates sFRP1 and Smad4 via demethylation and histone modification in prostate cancer cellsSemantic proximity Read ↗

MiR-377 inhibits the proliferation of pancreatic cancer by targeting Pim-3Semantic proximity Read ↗

Mir-183 functions as an oncogene via decreasing PTEN in breast cancer cellsSemantic proximity Read ↗

PLCD3 inhibits apoptosis and promotes proliferation, invasion and migration in gastric cancerSemantic proximity Read ↗

MicroRNA-375 targets PDK1 in pancreatic carcinoma and suppresses cell growth through the Akt signaling pathwaySemantic proximity Read ↗

Up-regulation of <i>miR-200</i> and <i>let-7</i> by Natural Agents Leads to the Reversal of Epithelial-to-Mesenchymal Transition in Gemcitabine-Resistant Pancreatic Cancer CellsSemantic proximity Read ↗

miR-223-3p regulates cell growth and apoptosis via FBXW7 suggesting an oncogenic role in human testicular germ cell tumorsSemantic proximity Read ↗

Intrinsic Chemoresistance to Gemcitabine Is Associated with Decreased Expression of BNIP3 in Pancreatic CancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.