Article
Loss of cAMP/CRP regulation confers extreme high hydrostatic pressure resistance in Escherichia coli O157:H7.
International journal of food microbiology - 16 Aug 2013
Vanlint Dietrich, Pype Brecht J Y, Rutten Nele, Vanoirbeek Kristof G A, Michiels Chris W, Aertsen Abram
Abstract excerpt
Application of high hydrostatic pressure (HHP) constitutes a valuable non-thermal pasteurization process in modern food conservation. Triggered by our interest in the rapid adaptive evolution towards HHP resistance in the food-borne pathogen E. coli O157:H7 (strain ATCC 43888) that was demonstrated earlier, we used genetic screening to identify specific loci in which a loss-of-function mutation would be...
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