Article
Genomic and phenotypic characterization of in vitro-generated Chlamydia trachomatis recombinants.
BMC microbiology - 20 Jun 2013
Jeffrey Brendan M, Suchland Robert J, Eriksen Steven G, Sandoz Kelsi M, Rockey Daniel D
Abstract excerpt
BACKGROUND: Pre-genomic and post-genomic studies demonstrate that chlamydiae actively recombine in vitro and in vivo, although the molecular and cellular biology of this process is not well understood. In this study, we determined the genome sequence of twelve Chlamydia trachomatis recombinants that were generated in vitro under antibiotic selection. These strains were used to explore the process of recombination...
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