Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Impacts and interactions of PDGFRB, MMP-3, TIMP-2, and RNF213 polymorphisms on the risk of Moyamoya disease in Han Chinese human subjects.

Gene - 10 Sept 2013

Wang Xiaomeng, Zhang Zhizhong, Liu Wenhua, Xiong Yunyun, Sun Wen, Huang Xianjun, Jiang Yongjun, Ni Guanzhong, Sun Wenshan, Zhou Lulu, Wu Li, Zhu Wusheng, Li Hua, Liu Xinfeng, Xu Gelin

Abstract excerpt

Polymorphisms of PDGFRB, MMP-3, TIMP-2, RNF213, TGFB1, Raptor and eNOS genes have been associated with Moyamoya disease (MMD) separately in studies, but their interactions on MMD have never been evaluated in one study. This study enrolled 96 MMD patients and 96 controls to evaluate the contributions and interactions of these polymorphisms on MMD in Chinese Hans. After genotyping, five polymorphisms loci were...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenosine Triphosphatases
Share to Asian People

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epistasis, Genetic

Share to Matrix Metalloproteinase 3

Share to Moyamoya Disease

Share to Receptor, Platelet-Derived Growth Factor beta

Share to Tissue Inhibitor of Metalloproteinase-2

Share to Ubiquitin-Protein Ligases

Source

Identifiers

PMID: 23769926
DOI: 10.1016/j.gene.2013.05.083

Genes

MMD
PDGFRB
TGFB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Impacts and interactions of PDGFRB, MMP-3, TIMP-2, and RNF213 polymorphisms on the risk of Moyamoya disease in Han Chinese human subjects.PMID 23769926Read ↗

Association of Genetic Variants With Moyamoya Disease in 13 000 Individuals: A Meta-Analysis.Semantic proximity Read ↗

Research Progresses in Understanding the Pathophysiology of Moyamoya Disease.Semantic proximity Read ↗

RNF213 polymorphism and Moyamoya disease: A systematic review and meta-analysis.Semantic proximity Read ↗

The Susceptibility Pathogenesis of Moyamoya Disease.Semantic proximity Read ↗

Rare variants of RNF213 and moyamoya/non-moyamoya intracranial artery stenosis/occlusion disease risk: a meta-analysis and systematic review.Semantic proximity Read ↗

The GC + CC genotype at position -418 in TIMP-2 promoter and the -1575GA/-1306CC genotype in MMP-2 is genetic predisposing factors for prevalence of moyamoya disease.Semantic proximity Read ↗

RNF213 p.R4810K Polymorphism and the Risk of Moyamoya Disease, Intracranial Major Artery Stenosis/Occlusion, and Quasi-Moyamoya Disease: A Meta-Analysis.Semantic proximity Read ↗

RNF213 as the major susceptibility gene for Chinese patients with moyamoya disease and its clinical relevance.Semantic proximity Read ↗

The RNF213 rs112735431 polymorphism might influence predisposition to moyamoya disease and exhibit different clinical features in Asian populationSemantic proximity Read ↗

Meta-analysis of genotype and phenotype studies to confirm the predictive role of the RNF213 p.R4810K variant for moyamoya disease.Semantic proximity Read ↗

Meta-analysis of the association between RNF213 polymorphisms and clinical features of moyamoya disease in Asian population.Semantic proximity Read ↗

RNF213 rs112735431 polymorphism in intracranial artery steno-occlusive disease and moyamoya disease in Koreans.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.