Article
Absence of familial defective apolipoprotein B-100 in Finnish patients with elevated serum cholesterol.
Atherosclerosis - 1 Jun 1990
Hämäläinen T, Palotie A, Aalto-Setälä K, Kontula K, Tikkanen M J
Abstract excerpt
Familial defective apolipoprotein B-100 is a genetic disorder which is associated with elevated plasma LDL levels. It appears to result from a G----A mutation at nucleotide 10,708 in exon 26 of the apolipoprotein B-100 gene leading to a substitution of glutamine for arginine at amino acid residue...
Topics
- Apolipoprotein B-100
- Apolipoproteins B
- Base Sequence
- DNA
- Enzyme-Linked Immunosorbent Assay
- Female
- Heterozygote
- Humans
- Hypercholesterolemia
- Hyperlipoproteinemia Type II
- Lipids
- Lipoproteins
- Male
- Molecular Sequence Data
- Mutation
- Polymerase Chain Reaction