Article
Absence of familial defective apolipoprotein B-100 in Finnish patients with elevated serum cholesterol.
Atherosclerosis - 1 Jun 1990
Hämäläinen T, Palotie A, Aalto-Setälä K, Kontula K, Tikkanen M J
Abstract excerpt
Familial defective apolipoprotein B-100 is a genetic disorder which is associated with elevated plasma LDL levels. It appears to result from a G----A mutation at nucleotide 10,708 in exon 26 of the apolipoprotein B-100 gene leading to a substitution of glutamine for arginine at amino acid residue 3500. We explored the possible role of this point mutation as a cause of elevated plasma cholesterol among the Finns,...
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