Article
Credibility analysis of putative disease-causing genes using bioinformatics.
PloS one - 1 Jan 2013
Abel Olubunmi, Powell John F, Andersen Peter M, Al-Chalabi Ammar
Abstract excerpt
BACKGROUND: Genetic studies are challenging in many complex diseases, particularly those with limited diagnostic certainty, low prevalence or of old age. The result is that genes may be reported as disease-causing with varying levels of evidence, and in some cases, the data may be so limited as to be indistinguishable from chance findings. When there are large numbers of such genes, an objective method for...
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