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Article

MAOA genotype, childhood maltreatment, and their interaction in the etiology of adult antisocial behaviors.

Biological psychiatry - 1 Jan 2014

Haberstick Brett C, Lessem Jeffrey M, Hewitt John K, Smolen Andrew, Hopfer Christian J, Halpern Carolyn T, Killeya-Jones Ley A, Boardman Jason D, Tabor Joyce, Siegler Ilene C, Williams Redford B, Mullan Harris Kathleen

Abstract excerpt

BACKGROUND: Maltreatment by an adult or caregiver during childhood is a prevalent and important predictor of antisocial behaviors in adulthood. A functional promoter polymorphism in the monoamine oxidase A (MAOA) gene has been implicated as a moderating factor in the relationship between childhood maltreatment and antisocial behaviors. Although there have been numerous attempts at replicating this observation,...

Topics

Adult
Black or African American
Antisocial Personality Disorder
Child
Child Abuse
Gene-Environment Interaction
Genetic Predisposition to Disease
Genotype
Humans
Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Monoamine Oxidase

White People

Source

Open in PubMed Open full text

Identifiers

PMID: 23726513
DOI: 10.1016/j.biopsych.2013.03.028
PMCID: PMC3815496

Genes

MAOA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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MAOA genotype, childhood maltreatment, and their interaction in the etiology of adult antisocial behaviors.PMID 23726513Read ↗

Childhood maltreatment, subsequent antisocial behavior, and the role of monoamine oxidase A genotype.Semantic proximity Read ↗

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MAOA, childhood maltreatment, and antisocial behavior: meta-analysis of a gene-environment interaction.Semantic proximity Read ↗

MAOA and the "cycle of violence:" childhood abuse and neglect, MAOA genotype, and risk for violent and antisocial behavior.Semantic proximity Read ↗

Maltreatment, MAOA, and delinquency: sex differences in gene-environment interaction in a large population-based cohort of adolescents.Semantic proximity Read ↗

MAOA, maltreatment, and gene-environment interaction predicting children's mental health: new evidence and a meta-analysis.Semantic proximity Read ↗

The effects of child maltreatment on early signs of antisocial behavior: genetic moderation by tryptophan hydroxylase, serotonin transporter, and monoamine oxidase A genes.Semantic proximity Read ↗

Interaction between MAO-A genotype and maltreatment in the risk for conduct disorder: failure to confirm in adolescent patients.Semantic proximity Read ↗

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No evidence for interaction between MAOA and childhood adversity for antisocial behavior.Semantic proximity Read ↗

Child abuse and neglect, MAOA, and mental health outcomes: a prospective examination.Semantic proximity Read ↗

Child maltreatment moderates the association of MAOA with symptoms of depression and antisocial personality disorder.Semantic proximity Read ↗

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