Article
Analysis of the inheritance pattern of a Chinese family with phaeochromocytomas through whole exome sequencing.
Gene - 10 Sept 2013
Cao Min, Sun Fukang, Huang Xin, Dai Jun, Cui Bin, Ning Guang
Abstract excerpt
Phaeochromocytomas (PCCs) and paragangliomas (PGLs) are rare, catecholamine-producing tumors. Most familial PCC/PGLs have been detected to be autosomal dominantly inherited. However, this study was undertaken in a family with PCCs to determine candidate genes in a dominant or recessive inheritance pattern. After excluding mutations in ten PCC/PGL susceptibility genes by Sanger sequencing, we used whole exome...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.