Article
Pleiotropy of FRIGIDA enhances the potential for multivariate adaptation.
Proceedings. Biological sciences - 22 Jul 2013
Lovell John T, Juenger Thomas E, Michaels Scott D, Lasky Jesse R, Platt Alexander, Richards James H, Yu Xuhong, Easlon Hsien M, Sen Saunak, McKay John K
Abstract excerpt
An evolutionary response to selection requires genetic variation; however, even if it exists, then the genetic details of the variation can constrain adaptation. In the simplest case, unlinked loci and uncorrelated phenotypes respond directly to multivariate selection and permit unrestricted paths to adaptive peaks. By contrast, 'antagonistic' pleiotropic loci may constrain adaptation by affecting variation of...
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