Article
Role of imatinib in the treatment of pediatric onset indolent systemic mastocytosis: a case report.
The Journal of dermatological treatment - 1 Dec 2013
Agarwala Manoj Kumar, George Renu, Mathews Vikram, Balasubramanian Poonkuzhali, Thomas Meera, Nair Sheila
Abstract excerpt
BACKGROUND: Mastocytosis is a sporadic disease characterized by an abnormal accumulation of mast cells (MCs) in single or multiple organs. It has a heterogeneous clinical picture which is a reflection of underlying tissue MC burden, mediators released and the organs involved. Here, the authors report significant symptomatic, cutaneous and systemic response to imatinib in a case of childhood onset indolent D816V...
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