Article
Comparison of metal ion-induced conformational changes in parvalbumin and oncomodulin as probed by the intrinsic fluorescence of tryptophan 102.
The Journal of biological chemistry - 15 Jul 1990
Hutnik C M, MacManus J P, Banville D, Szabo A G
Abstract excerpt
The calcium-induced conformational changes of the 108-amino acid residue proteins, cod III parvalbumin and oncomodulin, were compared using tryptophan as a sensitive spectroscopic probe. As native oncomodulin is devoid of tryptophan, site-specific mutagenesis was performed to create a mutant protein in which tryptophan was placed in the identical position (residue 102) as the single tryptophan residue in cod III...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.