Article
[Characteristics of the conditions for memory cell differentiation--the initial and enriched precursors of secondary cytotoxic T-lymphocytes (pCTL-2) specific for the histocompatibility class I molecule].
Biulleten' eksperimental'noi biologii i meditsiny - 1 Mar 1990
Brondz B D, Osipova T V, Aptikaeva G F, Kromin V V
Abstract excerpt
The in vivo induced pCTL-2 with phenotype L3T4- Lyt2- specific to the H-2Kb molecule, turn into effector CTL during 4 days in the mixed lymphocyte culture (with heat-treated donor stimulators) much more efficiently when donor and recipient are different from one another not only in MHC class I (anti-BIO, MBR BIO.AKM) but in I + II (Kb + Ib) ahti-C57BL/6 BIAD2(RIOI). The initial pCTL-2 differentiation in enhanced...
Topics
- Animals
- Cell Differentiation
- Cells, Cultured
- Immunization
- Lymphocyte Activation
- Major Histocompatibility Complex
- Mice
- Mice, Inbred Strains
- Phenotype
- Spleen