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Article

Molecular analysis of an outbreak of lethal postpartum sepsis caused by Streptococcus pyogenes.

Journal of clinical microbiology - 1 Jul 2013

Turner Claire E, Dryden Matthew, Holden Matthew T G, Davies Frances J, Lawrenson Richard A, Farzaneh Leili, Bentley Stephen D, Efstratiou Androulla, Sriskandan Shiranee

Abstract excerpt

Sepsis is now the leading direct cause of maternal death in the United Kingdom, and Streptococcus pyogenes is the leading pathogen. We combined conventional and genomic analyses to define the duration and scale of a lethal outbreak. Two postpartum deaths caused by S. pyogenes occurred within 24 h; one was characterized by bacteremia and shock and the other by hemorrhagic pneumonia. The women gave birth within...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23616448
DOI: 10.1128/JCM.00679-13
PMCID: PMC3697669

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