Ovulation in Drosophila is controlled by secretory cells of the female reproductive tract.

doi:10.7554/eLife.00415

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Article

Ovulation in Drosophila is controlled by secretory cells of the female reproductive tract.

eLife - 16 Apr 2013

Sun Jianjun, Spradling Allan C

Abstract excerpt

How oocytes are transferred into an oviduct with a receptive environment remains poorly known. We found that glands of the Drosophila female reproductive tract, spermathecae and/or parovaria, are required for ovulation and to promote sperm storage. Reducing total secretory cell number by interferring with Notch signaling during development blocked ovulation. Knocking down expression after adult eclosion of the...

Topics

Animals
Animals, Genetically Modified
DNA-Binding Proteins
Drosophila Proteins
Drosophila melanogaster
Female
Gene Expression Regulation
Male
Mutation
Nuclear Proteins
Oocytes
Oviducts

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Ovulation

Receptors, Notch

Receptors, Steroid

Signal Transduction

Spermatozoa

Transcription Factors

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Identifiers

PMID: 23599892
DOI: 10.7554/eLife.00415
PMCID: PMC3628084

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