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Article

Muscle-enriched microRNA miR-486 decreases in circulation in response to exercise in young men

1 Jan 2013

Abstract excerpt

BACKGROUND: MicroRNAs (miRNAs) are small non-coding RNAs involved in post-transcriptional gene regulation. miRNAs are taken in by intracellular exosomes, secreted into circulation, and taken up by other cells, where they regulate cellular functions. We hypothesized that muscle-enriched miRNAs existing in circulation mediate beneficial metabolic responses induced by exercise. To test this hypothesis, we measured...

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PMID: 23596423
DOI: 10.3389/fphys.2013.00080

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