Article
Head-to-head comparison of two transcription-mediated amplification assay versions for detection of hepatitis B virus, hepatitis C virus, and human immunodeficiency virus Type 1 in blood donors.
Transfusion - 1 Oct 2013
Grabarczyk Piotr, van Drimmelen Harry, Kopacz Aneta, Gdowska Jolanta, Liszewski Grzegorz, Piotrowski Dariusz, Górska Joanna, Kuśmierczyk Jolanta, Candotti Daniel, Lętowska Magdalena, Lelie Nico, Brojer Ewa
Abstract excerpt
BACKGROUND: The second triplex transcription-mediated amplification (TMA) assay version (Ultrio Plus, Novartis Diagnostics) uses an additional reagent enhancing the disruption of hepatitis B virus (HBV) particles and release of DNA for the target capture probe. This study compares the performance of this new assay version with the previous one (Ultrio). STUDY DESIGN AND METHODS: For analytical sensitivity...
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