Article
Behavioral and psychosocial responses to genomic testing for colorectal cancer risk.
Genomics - 1 Aug 2013
Graves Kristi D, Leventhal Kara-Grace, Nusbaum Rachel, Salehizadeh Yasmin, Hooker Gillian W, Peshkin Beth N, Butrick Morgan, Tuong William, Mathew Jeena, Goerlitz David, Fishman Mary B, Shields Peter G, Schwartz Marc D
Abstract excerpt
We conducted a translational genomic pilot study to evaluate the impact of genomic information related to colorectal cancer (CRC) risk on psychosocial, behavioral and communication outcomes. In 47 primary care participants, 96% opted for testing of three single nucleotide polymorphisms (SNPs) related to CRC risk. Participants averaged 2.5 of 6 possible SNP risk alleles (10% lifetime risk). At 3-months,...
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