Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Strategies for production of active eukaryotic proteins in bacterial expression system

12 Jan 2012

Abstract excerpt

Bacteria have long been the favorite expression system for recombinant protein production. However, the flaw of the system is that insoluble and inactive proteins are co-produced due to codon bias, protein folding, phosphorylation, glycosylation, mRNA stability and promoter strength. Factors are cited and the methods to convert to soluble and active proteins are described, for example a tight control of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Monoclonal and Polyclonal Antibodies Research
Share to Protein purification and stability
Share to Viral Infectious Diseases and Gene Expression in Insects

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 23569889
DOI: 10.1016/s2221-1691(11)60213-x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Strategies for production of active eukaryotic proteins in bacterial expression systemPMID 23569889Read ↗

Production of active eukaryotic proteins through bacterial expression systems: a review of the existing biotechnology strategiesSemantic proximity Read ↗

Recent developments in difficult protein expression: a guide to E. coli strains, promoters, and relevant host mutations.Semantic proximity Read ↗

Cell-free expression systems for eukaryotic protein productionSemantic proximity Read ↗

An Overview of the Parameters for Recombinant Protein Expression in Escherichia coliSemantic proximity Read ↗

Expression of membrane proteins at the Escherichia coli membrane for structural studies.Semantic proximity Read ↗

Strategies for the Production of Recombinant Protein in Escherichia coliSemantic proximity Read ↗

So you want to express your protein in Escherichia coli ?Semantic proximity Read ↗

A systematic approach for testing expression of human full-length proteins in cell-free expression systemsSemantic proximity Read ↗

Fusion tags for protein solubility, purification and immunogenicity in Escherichia coli: the novel Fh8 systemSemantic proximity Read ↗

Recombinant protein expression in Escherichia coli: advances and challengesSemantic proximity Read ↗

Recent advances in producing and selecting functional proteins by using cell-free translation.Semantic proximity Read ↗

A Comparative Analysis of Recombinant Protein Expression in Different Biofactories: Bacteria, Insect Cells and Plant SystemsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.