Article
Plasma RANTES, IL-10, and IL-8 levels in non-small-cell lung cancer patients treated with EGFR-TKIs.
BMC research notes - 8 Apr 2013
Umekawa Kanako, Kimura Tatsuo, Kudoh Shinzoh, Suzumura Tomohiro, Oka Takako, Nagata Misato, Mitsuoka Shigeki, Matsuura Kuniomi, Nakai Toshiyuki, Yoshimura Naruo, Kira Yukimi, Hirata Kazuto
Abstract excerpt
BACKGROUND: Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs), routinely used to treat advanced non-small-cell lung cancer (NSCLC) patients with activated EGFR mutations, are associated with excellent response and improved performance status. Recently, pro-inflammatory cytokines, such as regulated upon activation normal T cell expressed and secreted (RANTES), interleukin (IL)-10 and IL-8...
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