No mutations in the serotonin related TPH1 and HTR1B genes in patients with monogenic sclerosing bone disorders.

doi:10.1016/j.bone.2013.03.015

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Article

No mutations in the serotonin related TPH1 and HTR1B genes in patients with monogenic sclerosing bone disorders.

Bone - 1 Jul 2013

Boudin Eveline, Jennes Karen, de Freitas Fenna, Tegay David, Mortier Geert, Van Hul Wim

Abstract excerpt

Since the identification of LRP5 as the causative gene for the osteoporosis pseudoglioma syndrome (OPPG) as well as the high bone mass (HBM) phenotype, LRP5 and the Wnt/β-catenin signaling have been extensively studied for their role in the differentiation and proliferation of osteoblasts, in the apoptosis of osteoblasts and osteocytes and in the response of bone to mechanical loading. However, more recently the...

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Source

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Identifiers

PMID: 23563356
DOI: 10.1016/j.bone.2013.03.015

Genes

LRP5
TPH1
HBM
LRP4
SOST

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.