Article
Heterozygosity at the A625C polymorphic site of the MyD88 gene is associated with Mycobacterium bovis infection in cattle.
Infection and immunity - 1 Jun 2013
Capparelli Rosanna, De Chiara Francesco, Nocerino Nunzia, Medaglia Chiara, Di Costanzo Rosa, Ramunno Luigi, Capuano Federico, Casalinuovo Francesco, Di Matteo Antonio, Iannelli Domenico
Abstract excerpt
The study demonstrates that in cattle, animals heterozygous at the MyD88 A625C polymorphic marker have a 5-fold reduced risk for active pulmonary tuberculosis (odds ratio [OR] = 0.19; P = 6 × 10(-12)). The reduced risk, however, does not extend to animals with latent pulmonary tuberculosis (OR =...
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