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Proteomic Biomarkers for Ageing the Mosquito Aedes aegypti to Determine Risk of Pathogen Transmission

11 Mar 2013

Abstract excerpt

Biomarkers of the age of mosquitoes are required to determine the risk of transmission of various pathogens as each pathogen undergoes a period of extrinsic incubation in the mosquito host. Using the 2-D Difference Gel Electrophoresis (2-D DIGE) procedure, we investigated the abundance of up to 898 proteins from the Yellow Fever and dengue virus vector, Aedes aegypti, during ageing. By applying a mixed-effects...

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PMID: 23536806
DOI: 10.1371/journal.pone.0058656

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