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Article

Dual role of G-runs and hnRNP F in the regulation of a mutation-activated pseudoexon in the fibrinogen gamma-chain transcript.

PloS one - 1 Jan 2013

Rimoldi Valeria, Soldà Giulia, Asselta Rosanna, Spena Silvia, Stuani Cristiana, Buratti Emanuele, Duga Stefano

Abstract excerpt

Most pathological pseudoexon inclusion events originate from single activating mutations, suggesting that many intronic sequences are on the verge of becoming exons. However, the precise mechanisms controlling pseudoexon definition are still largely unexplored. Here, we investigated the cis-acting elements and trans-acting regulatory factors contributing to the regulation of a previously described fibrinogen...

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Identifiers

PMID: 23533617
DOI: 10.1371/journal.pone.0059333
PMCID: PMC3606458

Genes

FGG

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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