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Article

MicroRNAs in Human Placental Development and Pregnancy Complications

8 Mar 2013

Abstract excerpt

MicroRNAs (miRNAs) are small non-coding RNAs, which function as critical posttranscriptional regulators of gene expression by promoting mRNA degradation and translational inhibition. Placenta expresses many ubiquitous as well as specific miRNAs. These miRNAs regulate trophoblast cell differentiation, proliferation, apoptosis, invasion/migration, and angiogenesis, suggesting that miRNAs play important roles during...

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PMID: 23528856
DOI: 10.3390/ijms14035519

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