Article
Whole genome sequencing identifies zoonotic transmission of MRSA isolates with the novel mecA homologue mecC.
EMBO molecular medicine - 1 Apr 2013
Harrison Ewan M, Paterson Gavin K, Holden Matthew T G, Larsen Jesper, Stegger Marc, Larsen Anders Rhod, Petersen Andreas, Skov Robert L, Christensen Judit Marta, Bak Zeuthen Anne, Heltberg Ole, Harris Simon R, Zadoks Ruth N, Parkhill Julian, Peacock Sharon J, Holmes Mark A
Abstract excerpt
Several methicillin-resistant Staphylococcus aureus (MRSA) lineages that carry a novel mecA homologue (mecC) have recently been described in livestock and humans. In Denmark, two independent human cases of mecC-MRSA infection have been linked to a livestock reservoir. We investigated the molecular epidemiology of the associated MRSA isolates using whole genome sequencing (WGS). Single nucleotide polymorphisms...
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