Article
Polymorphism in the neurofibromin gene, Nf1, is associated with antagonistic selection on wing size and development time in Drosophila melanogaster.
Molecular ecology - 1 May 2013
Lee Siu F, Eyre-Walker Ying Chen, Rane Rahul V, Reuter Caroline, Vinti Giovanna, Rako Lea, Partridge Linda, Hoffmann Ary A
Abstract excerpt
In many invertebrates, body size shows genetically based clines, with size increasing in colder climates. Large body size is typically associated with prolonged development times. We consider variation in the CNS-specific gene neurofibromin 1 (Nf1) and its association with body size and development time. We identified two major Nf1 haplotypes in natural populations, Nf1-insertion-A and Nf1-deletion-G. These...
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