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A Zebrafish Model of Diabetes Mellitus and Metabolic Memory

28 Feb 2013

Abstract excerpt

Diabetes mellitus currently affects 346 million individuals and this is projected to increase to 400 million by 2030. Evidence from both the laboratory and large scale clinical trials has revealed that diabetic complications progress unimpeded via the phenomenon of metabolic memory even when glycemic control is pharmaceutically achieved. Gene expression can be stably altered through epigenetic changes which not...

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PMID: 23485929
DOI: 10.3791/50232

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