Article
Molecular alterations in partially-encapsulated or well-circumscribed follicular variant of papillary thyroid carcinoma.
Thyroid : official journal of the American Thyroid Association - 1 Oct 2013
Howitt Brooke E, Jia Yonghui, Sholl Lynette M, Barletta Justine A
Abstract excerpt
BACKGROUND: Studies have described an encapsulated and an infiltrative form of the follicular variant of papillary thyroid carcinoma (FVPTC). Encapsulated FVPTCs have been reported to have virtually no recurrence risk or metastatic potential and to harbor RAS mutations but not BRAF mutations. In contrast, infiltrative tumors have significant metastatic potential, a risk of recurrence, and a BRAF mutation...
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