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Aldehyde dehydrogenasehigh gastric cancer stem cells are resistant to chemotherapy

22 Feb 2013

Abstract excerpt

Cancer stem cells (CSCs) are known to influence chemoresistance, survival, relapse and metastasis. Aldehyde dehydrogenase (ALDH) functions as an epithelial CSC marker. In the present study, we investigated the involvement of ALDH in gastric CSC maintenance, chemoresistance and survival. Following screening for eight candidate markers (CD13, CD26, CD44, CD90, CD117, CD133, EpCAM and ALDH), five gastric cancer cell...

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PMID: 23440340
DOI: 10.3892/ijo.2013.1837

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