Article
Lessons from Dwarf8 on the strengths and weaknesses of structured association mapping.
PLoS genetics - 1 Jan 2013
Larsson Sara J, Lipka Alexander E, Buckler Edward S
Abstract excerpt
The strengths of association mapping lie in its resolution and allelic richness, but spurious associations arising from historical relationships and selection patterns need to be accounted for in statistical analyses. Here we reanalyze one of the first generation structured association mapping studies of the Dwarf8 (d8) locus with flowering time in maize using the full range of new mapping populations,...
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