Article
Phase II trial of bevacizumab and satraplatin in docetaxel-pretreated metastatic castrate-resistant prostate cancer.
Urologic oncology - 1 Jan 2014
Vaishampayan Ulka N, Fontana Joseph, Heilbrun Lance K, Smith Daryn, Heath Elisabeth, Dickow Brenda, Figg William D
Abstract excerpt
BACKGROUND: Satraplatin is an oral platinum compound that has demonstrated efficacy and tolerability in prostate cancer. Preclinical synergy between bevacizumab and platinum has been noted. METHODS: Docetaxel-pretreated metastatic castrate-resistant prostate cancer patients with disease progression were eligible. Satraplatin 80 mg/m(2) orally on days 1 to 5, prednisone 5mg twice daily, and bevacizumab 10mg/kg on...
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