Article
Identification of Novel Type III Secretion Chaperone-Substrate Complexes of Chlamydia trachomatis
19 Feb 2013
Abstract excerpt
Chlamydia trachomatis is an obligate intracellular bacterial pathogen of humans that uses a type III secretion (T3S) system to manipulate host cells through the delivery of effector proteins into their cytosol and membranes. The function of T3S systems depends on small bacterial cytosolic chaperone-like proteins, which bind T3S substrates and ensure their appropriate secretion. To find novel T3S...
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